When prescribing levothyroxine therapy for the elderly, which statement is true?

The choice stating that "presentation of thyroxine excess may include worsening angina symptoms" is accurate because levothyroxine, a synthetic form of the thyroid hormone thyroxine (T4), can lead to symptoms of hyperthyroidism if administered in excess. In elderly patients, especially those with pre-existing cardiovascular conditions, such as angina or coronary artery disease, even mild excess of thyroid hormone can exacerbate these conditions. This is due to the increased metabolic demand and enhanced cardiac output associated with elevated thyroid hormone levels, which can lead to increased heart rate, palpitations, and chest pain. Therefore, it is crucial to monitor elderly patients closely when initiating levothyroxine therapy and adjust dosage carefully to avoid complications such as worsening angina. This highlights the need for cautious treatment approaches tailored to the elderly population.