When prescribing an SSRI, what should the nurse practitioner consider?

In considering the use of selective serotonin reuptake inhibitors (SSRIs), recognizing the common side effects associated with their initiation is essential for managing patient expectations and monitoring progress. The correct answer highlights that mild gastrointestinal (GI) upset is often reported during the first weeks of SSRI use. This side effect is a result of the drug's mechanism of action, which increases serotonin levels not only in the brain but also affects serotonin receptors in the gut. Consequently, patients may experience nausea, diarrhea, or other forms of gastrointestinal distress initially, which often resolve as the body adjusts to the medication.

Understanding this aspect is crucial for healthcare providers, as it allows them to educate patients about what to expect and to reassure them that these symptoms are typically transient. It also underscores the importance of monitoring patients during the early stages of treatment to help alleviate any concerns they may have. This proactive approach enhances patient adherence to the treatment plan, leading to better long-term outcomes.