When considering the use of a second-generation antipsychotic for an elder with Alzheimer-type dementia, what concern is significant?

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The significant concern when using a second-generation antipsychotic for an elder with Alzheimer-type dementia lies in the increased risk of stroke and cardiovascular events. This is particularly important in older adults who may already have underlying health issues, making them more susceptible to these serious side effects. Research has shown that while these medications may be used to manage certain behavioral symptoms associated with dementia, they are associated with an elevated risk of adverse cardiovascular outcomes, such as strokes and heart-related incidents.

Additionally, the other options do not accurately reflect the primary concern in this context. For example, while there may be discussions surrounding the potential of certain treatments to slow the progression of Alzheimer’s disease, this is not the primary concern with the use of antipsychotics. Using these medications is not automatically contraindicated in patients with Alzheimer’s, although careful consideration and monitoring are essential; moreover, starting at a higher dose is typically not advisable due to the risk of exacerbating side effects. Therefore, the emphasis on the increased risk of stroke and cardiovascular events makes this a critical consideration when prescribing such medications to this vulnerable population.

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